Klotho Prices

Klotho price per mg by vendor

Prices last collected October 3, 2026. Prices change often - check the vendor's site before ordering.

About Klotho

What it is

Klotho, also called alpha-Klotho, is a protein made mainly in the kidney and brain that acts as a co-receptor for FGF23 and circulates in a soluble form linked to aging. In animal studies, higher Klotho extends lifespan and protects the kidneys, blood vessels, and brain, while low levels track with age-related disease. It is an endogenous protein under investigation with no approved therapeutic form, and most human evidence is observational.

How it works

It acts as an FGF23 co-receptor and, in soluble form, regulates phosphate handling and inhibits IGF-1, Wnt, and TGF-beta signaling.

Researched for

Longevity research; kidney protection; cognitive aging; vascular health

Half-life

Not established in humans

Familiarity

Advanced

Research evidence

Animal studies only

Regulatory status

Preclinical

Key risk

None documented

Disclosure. Some vendors above are Peptul partners and pay us a commission when you buy through our link. Rows are ordered by: Peptul partners first, then what is in stock, then single vials before multi-vial packs, then price per milligram. Paying us moves a vendor up this order and changes nothing else - not their trust tier, COA badge, Peptul Score or reviews, which come from evidence and are worked out the same way for everyone. Available discount codes are shown beside the prices above. Discounted prices require the displayed code where indicated.

For educational and research purposes only. Not medical advice. Always consult a qualified healthcare provider before using any research compound.