PE-22-28 Prices

Also known as Spadin analog; TREK-1 blocker

16 listings from 13 vendors, normalised to one honest price per milligram.

Cheapest per mg
$0.65/mg
At
BeiBangAn
Vendors
13
Sizes
8mg, 10mg Kit (10 vials), 10mg

Disclosure. Some vendors below are Peptul partners and pay us a commission when you buy through our link. Rows here are ordered by price per milligram only - paying us never moves a vendor up. Current discount codes are shown on the full price board.

PE-22-28 price per mg by vendor

Prices last collected August 19, 2026.

VendorSizePricePer mg
BeiBangAnVerified COA10mg Kit (10 vials)$65.00$0.65View
Hybiopeptides (HYB Peptides)Verified COA10mg Kit (10 vials)$95.00$0.95View
PeptidologyVerified COAShips US10mg$49.99$5.00View
Modern AminosVerified COAShips US10mg$54.00$5.40View
Paramount PeptidesVerified COAShips US10mg$55.25$5.53View
VPeptide CanadaVerified COA10mg Kit (10 vials)$576.62$5.77View
Huaian Hanyou PeptideVerified COA8mg$50.00$6.25View
Cocer PeptidesVerified COAShips US8mg$54.00$6.75View
Biotech PeptidesVerified COAShips US8mg$55.00$6.88View
Raw AminoVerified COAShips US8mg$55.00$6.88View
Umbrella LabsVerified COAShips US10mg$70.99$7.10View
SimplePeptideVerified COAShips US10mg$72.00$7.20View
VPeptide CanadaVerified COA10mg$72.08$7.21View
Behemoth LabzVerified COAShips US8mg$67.17$8.40View
Behemoth LabzVerified COAShips US10mg$84.09$8.41View

About PE-22-28

What it is
PE-22-28 is a synthetic seven amino acid peptide derived from spadin, a fragment of the sortilin propeptide. In rodent and laboratory studies it blocks the TREK-1 potassium channel with high potency and produced antidepressant-like effects along with signs of increased hippocampal neurogenesis. It has not been tested in humans and remains an investigational research compound.
How it works
It inhibits the TREK-1 potassium channel, an action linked in animal models to antidepressant effects and enhanced neurogenesis.
Researched for
Depression research; neurogenesis research; TREK-1 studies
Half-life
Not established in humans
Familiarity
Advanced
Research evidence
Animal studies only
Regulatory status
Preclinical
Key risk
None documented

For educational and research purposes only. Not medical advice. Always consult a qualified healthcare provider before using any research compound.